Or you could soak it in prescription strength urea for a couple of days to get the nail to fall off. Less collateral damage that way.

OP might be talking about a procedure where a podiatrist or dermatologist kills the mis-growing edges of the nail root. The remaining root grows a narrower nail, but hopefully a straighter one. Sometimes the process doesn’t work the first time (hard to judge how much cell-kill stuff will get just the edges and not damage the middle) and has to be repeated.

It’s a war of attrition at this point, with Ukraine providing almost all the people to become casualties but highly dependent on foreign aid for weapons, ammunition, intelligence, and continued sanctions enforcement on Russia. If either the foreign support or the domestic supply of soldiers falls short before the Russian economy collapses, Russia gets to keep the occupied land. If the first break is the ruble tanks to the point desperate poor foreigners stop signing up en masse to be cannon fodder in the Russian army, Ukraine could realistically take back the territory they lost.

Arguably Bernie got as many primary votes as he did (a good showing but a legitimate loss) because inside politics had cleared the field of more compelling challengers to Clinton. https://www.vox.com/policy-and-politics/2017/11/14/16640082/donna-brazile-warren-bernie-sanders-democratic-primary-rigged

That’s interesting, I hadn’t realized they affected some people that way. I have noticed their “beef” and “pork” products include a lot of fat, maybe the greasy slipperiness contributes to the effect? I’d like to think use in dishes where the other ingredients are low-fat would balance things out, but if not that’s sad for that brand.

I am sure it will enjoy economies of scale. Lab grown meat is currently something like 1000x the cost of animal-grown meat: I am confident they can get that down to 10x, maybe single digits. I am equally confident the inherent inefficiency of growing muscle cells without the integrated functions of the rest of the animal mean the lab cost will never be lower.

The barrier here is that hundreds of millions of years of animal evolution has extremely optimized their form, and the nature of growing only the muscle cells de-optimizes the system. Animals have immune systems; lab cells have to be kept in a sterile environment, a significant cost. Animals have digestive systems and can power cell growth and all other functions from common plant materials; lab cells have to be fed pre-digested and carefully proportioned material, a significant cost. Animals have circulatory systems that efficiently perfuse oxygen and nutrients, and remove waste; lab cell containers have to be centrifuged in small containers because the forces required in large containers damage the cells. And so on.

Lab-grown cuts are sold as a luxury good now, and I expect as the price comes down from 1000x animal-grown meat to more like 10x animal-grown meat they will become more widely eaten by rich conspicuous consumers.

The real opportunity for equal-tasting, cheaper, better for the environment “meat” is development of and efficiencies gained by scaling the lines of plant-based imitations like what Impossible and it’s competitors are doing.

Lab grown animal cells will always be more expensive than animal-grown animal cells. Animals have immune systems; lab cells have to be kept in a sterile environment, a significant cost. Animals have digestive systems and can power cell growth and all other functions from common plant materials; lab cells have to be fed pre-digested and carefully proportioned material, a significant cost. Animals have circulatory systems that efficiently perfuse oxygen and nutrients, and remove waste; lab cell containers have to be centrifuged in small containers because the forces required in large containers damage the cells. And so on.

The real potential for equal-tasting, cheaper, better-for-environment cuts is in plant-based imitations like what Impossible brand and its competitors are doing.

These laws banning lab grown cells are banning designer lab-grown cuts as a luxury good. Once that market matures, I am sure the wealthy people who jump on the conspicuous consumption bandwagon will not have any problem getting the law repealed or exceptions carved out for them.

An economic podcast I listen to has covered how much foreign investment the US net trade imbalance has led to, for exactly that reason: foreigners had dollars from US entities buying more stuff than they sold, those dollars had to come back to the US, and investment ended up being a huge way that happened. If the trade imbalance actually reduces, likely that investment rate will be the first thing to drop. We’ve already seen hints of it with softened demand for Treasury bonds.

The US has had relatively steady population growth for so long, all our normal ranges for economic indicators have an assumption of a growing population baked in, including what a healthy amount of GDP growth is - enough to both cover the prior GDP per person for the new people, and also have some productivity growth.

This year with all the immigration policy changes (and maybe some emigration pattern changes), projections are for a population decline. Which means potentially GDP could maintain or slightly improve on a per-capita basis, and yet decline overall.

The current policies are doing damage that will last at a minimum of decades, but I think it’s important to try to sort out the real damage from the weirdness of massive change. If we manage to get a majority of elected officials who actually want to do repairs, good analysis will be important to figuring out best bang for resources to focus on.

It was weirder than that. Hawley was pitching income-based check distribution (full amount for annual income below $75,000 then phased to lower amounts up to $200,000 or something like that). Then he stated that this policy of income restrictions would ensure everyone who got a check would be Republican (meaning, no Republican makes more than $200,000 a year) and would prevent Democrats from getting checks (meaning, all Democrats make more than $200,000 a year). It breaks my brain.

Not only is moderation expensive, but the current administration has attacked organizations that try to moderate anyone who catches the fancy of the MAGAverse. Slash moderation departments and reduce the risk of expensive lawsuits and harassment with the power of the federal government behind it, win-win.

Their belief in MAGA is filling some deep psychological need. Logical reasoning around the belief is irrelevant because logic can’t activate whatever social buttons are being satisfied by their engagement with the MAGA movement.

Research trying to figure out what makes humans susceptible to this kind of stuff and how to protect each other was a hot topic, but then Congressional Republicans launched harassing investigations into everyone in the field and the institutions that supported their work, and of course the current executive branch has entrenched that fear. Gotta keep the victims coming to the grifter trough.

I think I have learned about seven separate ticketing systems at my work, so far. The specialized ones are associated with small teams I know and can go harass if they don’t answer in a reasonable time frame. The big main one, the associates reliably answer quickly, to let me know they can’t help me. It all feels very broken.

Different people and relationships can have different solutions that work for them. That’s OK!

There isn’t a list of abusers. The only person the files have evidence of abuse is Epstein himself. Per multiple sources interviewed by the NY Times, the only lists in the files are victims and witnesses, and releasing the files would just victimize them again to doxxing. https://www.nytimes.com/2025/07/24/us/politics/epstein-files-trump-bondi-justice-department-fbi.html

Dems are jumping on the bandwagon because it distracts the Republicans from their rampage of destroying the foundations of our country, but the files themselves are a nothingburger as far any actual evidence of crimes.

https://clerk.house.gov/Members/ViewVacancies

Gerald Connolly and Raúl M. Grijalva, apparently. Both were Democrats. No, there are no alternates. Each State determines its own process for filling vacancies: often the governor appoints someone but special elections are also common.

“We need to be cautious!” would be much more compelling if the standard medical approach to trans minors was not already immensely cautious.

The standard may be cautious, but a significant number of individual clinicians are not. But pointing out that a concerning number of care providers have looser-than-standard medical approaches gets the speaker attacked as a traitor to the cause.

Bolding mine, quite from https://www.theatlantic.com/ideas/archive/2025/06/transgender-youth-skrmetti/683350/

When red-state bans are discussed, you will also hear liberals say that conservative fears about the medical-transition pathway are overwrought—because all children get extensive, personalized assessments before being prescribed blockers or hormones. This, too, is untrue. Although the official standards of care recommend thorough assessment over several months, many American clinics say they will prescribe blockers on a first visit.